Concepedia

Julie M. Crudele

JM

Statistics

Publications

6

Citations

660

H-Index

6

Active since

2010

Affiliations

University of Pennsylvania(Current)

Children's Hospital of Philadelphia

University of Washington

University of North Carolina at Chapel Hill

Julie M. Crudele is an author at University of Pennsylvania specializing in molecular signaling, protein engineering, and vascular biology.

ORCID

Top concepts

Publications per year

2010–2023

6

Publications

6

Cas9 immunity creates challenges for CRISPR gene editing therapies

Julie M. Crudele, Jeffrey S. Chamberlain · Nature Communications · 2018 · 244 citations · Full text

Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy

Jonathan D. Finn, Margareth C. Ozelo, Denise E. Sabatino et al. · Blood · 2010 · 153 citations · Full text

AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice

Julie M. Crudele, Jonathan D. Finn, Joshua Siner et al. · Blood · 2015 · 151 citations · Full text

Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy

Sharla M. Birch, Michael W. Lawlor, Thomas J. Conlon et al. · Science Translational Medicine · 2023 · 64 citations · Full text

Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models

Joshua Siner, Benjamin J. Samelson‐Jones, Julie M. Crudele et al. · JCI Insight · 2016 · 36 citations · Full text

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