Alfred Singer

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

Life Sciences, Cell Biology, Immunology +17

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2

Xuguang Tai, Michelle L. Cowan, Lionel Feigenbaum et al. · Nature Immunology · 2005 · 592 citations

Life Sciences, Cell Biology, Immunology +17

Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines

Jung‐Hyun Park, Qing Yu, Batu Erman et al. · Immunity · 2004 · 485 citations · Full text

Life Sciences, Immunology, Pathology +14

Coreceptor Reversal in the Thymus

Enrico Brugnera, Avinash Bhandoola, Ricardo Cibotti et al. · Immunity · 2000 · 258 citations · Full text

Life Sciences, Immunology, Physiology +7

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28.

Jennifer A. Punt, Barbara A. Osborne, Yousuke Takahama et al. · The Journal of Experimental Medicine · 1994 · 251 citations · Full text

Life Sciences, Cell Biology, Immunology +17