Barbara A. Osborne

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77

Zheng-gang Liu, Sallie W. Smith, Kelly A. McLaughlin et al. · Nature · 1994 · 551 citations

Signal Transduction, Developmental Biology, Signaling Pathway +11

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

Sanne Weijzen, Paola Rizzo, Mike Braid et al. · Nature Medicine · 2002 · 546 citations

Tumor Biology, Human Ras-transformed Cells, Lineage Plasticity +11

Proteasomes play an essential role in thymocyte apoptosis.

Lisa Grimm, Alfred L. Goldberg, Guy G. Poirier et al. · The EMBO Journal · 1996 · 314 citations · Full text

Protein Function, Medicine, Apoptosis +6

Notch1 augments NF‐κB activity by facilitating its nuclear retention

Hyun Mu Shin, Lisa M. Minter, Ok Hyun Cho et al. · The EMBO Journal · 2005 · 296 citations · Full text

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21.

Lisa M. Minter, Danielle M. Turley, Pritam Das et al. · PubMed · 2005 · 279 citations