Guy G. Poirier

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

Life Sciences, Biochemistry, Molecular Biology +10

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

Muneesh Tewari, Long T. Quan, Karen O’Rourke et al. · Cell · 1995 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Scott H. Kaufmann, Serge Desnoyers, Yvonne Ottaviano et al. · PubMed · 1993 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +14

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Damien D’Amours, Serge Desnoyers, Icy D’Silva et al. · Biochemical Journal · 1999 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

Seong-Woon Yu, Hongmin Wang, Marc F. Poitras et al. · Science · 2002 · 1.8K citations

Life Sciences, Cell Biology, Molecular Biology +15