Michael J. Shapiro

1,3- diastereoselective reduction of β-hydroxyketones utilizing alkoxydialkylboranes

Kau-Ming Chen, G. E. HARDTMANN, Kapa Prasad et al. · Tetrahedron Letters · 1987 · 430 citations

1,3- Diastereoselective Reduction, Organic Chemistry, Chemistry +2

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides

Gilles H. Goetz, Laurence Philippe, Michael J. Shapiro · ACS Medicinal Chemistry Letters · 2014 · 149 citations

Engineering, Supercritical Fluid Chromatography, Peptide Engineering +22

NOE Pumping:  A Novel NMR Technique for Identification of Compounds with Binding Affinity to Macromolecules

Aidi Chen, Michael J. Shapiro · Journal of the American Chemical Society · 1998 · 144 citations

Drug Target, Binding Affinity, Altmetric Attention Score +23

The effect of relaxation on the epitope mapping by saturation transfer difference NMR

Jiangli Yan, Allen D. Kline, Huaping Mo et al. · Journal of Magnetic Resonance · 2003 · 134 citations

Biophysical Modeling, Magnetic Resonance Spectroscopy, Electron Paramagnetic Resonance +8