Laurence Philippe

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides

Gilles H. Goetz, Laurence Philippe, Michael J. Shapiro · ACS Medicinal Chemistry Letters · 2014 · 149 citations

Engineering, Supercritical Fluid Chromatography, Peptide Engineering +22

High Throughput Method for the Indirect Detection of Intramolecular Hydrogen Bonding

Gilles H. Goetz, William Farrell, Marina Shalaeva et al. · Journal of Medicinal Chemistry · 2014 · 106 citations

Engineering, Supercritical Fluid Chromatography, Chemistry +24

Integrating Intramolecular Hydrogen Bonding (IMHB) Considerations in Drug Discovery Using ΔlogP As a Tool

Marina Shalaeva, Giulia Caron, Yuriy A. Abramov et al. · Journal of Medicinal Chemistry · 2013 · 85 citations · Full text

Reliable δLogp, Drug Target, Computational δLogp +19

Biaryl-Bridged Macrocyclic Peptides: Conformational Constraint via Carbogenic Fusion of Natural Amino Acid Side Chains

Falco‐Magnus Meyer, James C. Collins, Brendan N. Borin et al. · The Journal of Organic Chemistry · 2012 · 60 citations

Aryl Boronate, Medicinal Chemistry, Biochemistry +14