Jiangli Yan

Discovery of Clinical Candidate 1-{[(2 <i>S</i> ,3 <i>S</i> ,4 <i>S</i> )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design

Katherine L. Lee, Catherine M. Ambler, David R. Anderson et al. · Journal of Medicinal Chemistry · 2017 · 138 citations · Full text

The effect of relaxation on the epitope mapping by saturation transfer difference NMR

Jiangli Yan, Allen D. Kline, Huaping Mo et al. · Journal of Magnetic Resonance · 2003 · 134 citations

Biophysical Modeling, Magnetic Resonance Spectroscopy, Electron Paramagnetic Resonance +8

High Throughput Method for the Indirect Detection of Intramolecular Hydrogen Bonding

Gilles H. Goetz, William Farrell, Marina Shalaeva et al. · Journal of Medicinal Chemistry · 2014 · 106 citations

Engineering, Supercritical Fluid Chromatography, Chemistry +24

Complete Relative Stereochemistry of Multiple Stereocenters Using Only Residual Dipolar Couplings

Jiangli Yan, Frank Delaglio, Andreas Kaerner et al. · Journal of the American Chemical Society · 2004 · 85 citations

Nearby Rdcs, Biochemistry, Natural Sciences +8

A Novel Method for the Determination of Stereochemistry in Six-Membered Chairlike Rings Using Residual Dipolar Couplings

Jiangli Yan, Allen D. Kline, Huaping Mo et al. · The Journal of Organic Chemistry · 2003 · 79 citations

Novel Method, Engineering, Heterocyclic +13