Michał Biśta

Lifeact: a versatile marker to visualize F-actin

Julia Riedl, Álvaro H. Crevenna, Kai Kessenbrock et al. · Nature Methods · 2008 · 2.2K citations · Full text

Protein Function, Cell Signaling, Medicine +10

Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival

Jason G. Kettle, Husam Alwan, Michał Biśta et al. · Journal of Medicinal Chemistry · 2016 · 135 citations · Full text

Tool Compounds, Chemoprevention Strategy, Selective Inhibitors +18

Robust Generation of Lead Compounds for Protein–Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists

Anna Czarna, Barbara Beck, Stuti Srivastava et al. · Angewandte Chemie International Edition · 2010 · 133 citations · Full text

Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs

Jeffrey W. Johannes, Amber Balazs, Derek Barratt et al. · Journal of Medicinal Chemistry · 2021 · 129 citations · Full text

Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists

David Ryan Koes, Kareem Khoury, Yijun Huang et al. · PLoS ONE · 2012 · 103 citations · Full text

Drug Target, Hit Identification, Molecular Biology +20