Kareem Khoury

Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists

David Ryan Koes, Kareem Khoury, Yijun Huang et al. · PLoS ONE · 2012 · 103 citations · Full text

Drug Target, Hit Identification, Molecular Biology +20

The p53-MDM2/MDMX axis – A chemotype perspective

Kareem Khoury, Grzegorz M. Popowicz, Tad A. Holak et al. · MedChemComm · 2011 · 66 citations · Full text

Molecular Docking, P53 Interaction, Functional P53 +14

Multicomponent Synthesis of Diverse 1,4-Benzodiazepine Scaffolds

Yijun Huang, Kareem Khoury, Tyler Chanas et al. · Organic Letters · 2012 · 64 citations · Full text

One-pot Mcrs, Combinatorial Chemistry, Medicinal Chemistry +13

Transient Protein States in Designing Inhibitors of the MDM2-p53 Interaction

Michał Biśta, Siglinde Wolf, Kareem Khoury et al. · Structure · 2013 · 59 citations · Full text

Medicine, Transient Protein States, Rational Drug Design +7

Efficient Assembly of Iminodicarboxamides by a “Truly” Four‐Component Reaction

Kareem Khoury, Mantosh K. Sinha, Tadamichi Nagashima et al. · Angewandte Chemie International Edition · 2012 · 53 citations

Combinatorial Chemistry, Organic Chemistry, Peptide Science +17