Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

Kazuhiro Hasegawa, Shu Wakino, Petra Šimić, +12

Nature Medicine

Diabetic AlbuminuriaUrologyRenal Tubular Sirt1Renal FunctionMedicine +7

NNMT activation can contribute to the development of fatty liver disease by modulating the NAD + metabolism

Motoaki Komatsu, Takeshi Kanda, Hidenori Urai, +10

Scientific Reports

Stair climbing/descending exercise for a short time decreases blood glucose levels after a meal in people with type 2 diabetes

Hiroto Honda, Makoto Igaki, Yuki Hatanaka, +6

BMJ Open Diabetes Research & Care

The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease

Rina Takahashi, Takeshi Kanda, Motoaki Komatsu, +16

Scientific Reports

Renal PathologyRenal InflammationNicotinamide Adenine DinucleotideRenal FunctionIga Glomerulonephritis +19

Ghrelin Protects against Renal Damages Induced by Angiotensin-II via an Antioxidative Stress Mechanism in Mice

Keiko Fujimura, Shu Wakino, Hitoshi Minakuchi, +10

PLoS ONE

Lipid PeroxidationRenal PathologyRenal InflammationReactive Oxygen SpeciesOxidative Stress +23

Insulin resistance in chronic kidney disease is ameliorated by spironolactone in rats and humans

Kozi Hosoya, Hitoshi Minakuchi, Shu Wakino, +11

Kidney International

Insulin ResistanceMetabolic SyndromeRenal FunctionMedicinePhysiology +9

The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1‐dependent mechanism in mice

Kazuhiro Hasegawa, Shu Wakino, Masumi Kimoto, +9

The FASEB Journal

Factors associated with SARS-CoV-2 antibody titers and prognosis of breakthrough infection in hemodialysis patients

Masataro Toda, Ayumi Yoshifuji, Kan Kikuchi, +7

Clinical and Experimental Nephrology

HemodialysisMedicineKidney FailureImmunologySars-cov-2 Antibody Titers +5

A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma

Ai Kato, Ayumi Yoshifuji, Kohji Komori, +8

Journal of Infection and Chemotherapy

Multiple MyelomaMicrobiologyMedicineClinical MicrobiologyNatto Bacteremia +1

Repeated 3-minute stair climbing-descending exercise after a meal over 2 weeks increases serum 1,5-anhydroglucitol levels in people with type 2 diabetes

Hiroto Honda, Makoto Igaki, Yuki Hatanaka, +6

Journal of Physical Therapy Science

Physical ActivityStair Climbing-descending ExerciseMetabolic SyndromeKinesiologyExercise +18