Hitoshi Minakuchi

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

Kazuhiro Hasegawa, Shu Wakino, Petra Šimić et al. · Nature Medicine · 2013 · 480 citations

Medicine, Molecular Biology, Nephrology +16

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

Kazuhiro Hasegawa, Shu Wakino, Kyoko Yoshioka et al. · Biochemical and Biophysical Research Communications · 2008 · 232 citations

Life Sciences, Biochemistry, Molecular Biology +14

Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function

Kazuhiro Hasegawa, Shu Wakino, Kyoko Yoshioka et al. · Journal of Biological Chemistry · 2010 · 221 citations · Full text

Life Sciences, Cell Biology, Apoptosis +9

High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection

Hiroyuki Umino, Kazuhiro Hasegawa, Hitoshi Minakuchi et al. · Scientific Reports · 2018 · 160 citations · Full text

Life Sciences, Cell Biology, Physiology +17

Rho and Rho-Kinase Activity in Adipocytes Contributes to a Vicious Cycle in Obesity That May Involve Mechanical Stretch

Yoshikazu Hara, Shu Wakino, Yoshiyuki Tanabe et al. · Science Signaling · 2011 · 109 citations

Life Sciences, Cell Biology, Physiology +16