Monica Castanedes‐Casey

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

Yong‐Jie Zhang, Ya-Fei Xu, Casey Cook et al. · Proceedings of the National Academy of Sciences · 2009 · 616 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS

Tania F. Gendron, Kevin F. Bieniek, Yong‐Jie Zhang et al. · Acta Neuropathologica · 2013 · 589 citations · Full text

Life Sciences, Genetics, Neurology +17

<i>C9ORF72</i> repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits

Jeannie Chew, Tania F. Gendron, Mercedes Prudencio et al. · Science · 2015 · 402 citations · Full text

Life Sciences, Genetics, Neurology +17

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

Yong‐Jie Zhang, Karen Jansen‐West, Ya-Fei Xu et al. · Acta Neuropathologica · 2014 · 340 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

Yong‐Jie Zhang, Tania F. Gendron, Mark Ebbert et al. · Nature Medicine · 2018 · 339 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17