Jeannie Chew

Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS

Tania F. Gendron, Kevin F. Bieniek, Yong‐Jie Zhang et al. · Acta Neuropathologica · 2013 · 575 citations · Full text

Chromatin, Neurodegenerative Diseases, Rna Processing +14

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

Bahareh Eftekharzadeh, J. Gavin Daigle, Larisa E. Kapinos et al. · Neuron · 2018 · 423 citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Neuroscience +8

<i>C9ORF72</i> repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits

Jeannie Chew, Tania F. Gendron, Mercedes Prudencio et al. · Science · 2015 · 396 citations · Full text

Mouse Brains, Synaptic Signaling, Social Sciences +17

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Zhaoming Su, Yong‐Jie Zhang, Tania F. Gendron et al. · Neuron · 2014 · 353 citations · Full text

Amyotrophic Lateral Sclerosis, Molecular Biology, Lead Small Molecules +2

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

Yong‐Jie Zhang, Karen Jansen‐West, Ya-Fei Xu et al. · Acta Neuropathologica · 2014 · 336 citations · Full text

Genetics, Aggregation-prone C9ftd/als Poly, Molecular Biology +17