Kaitlyn Shank

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

Olga A. Guryanova, Kaitlyn Shank, Barbara Spitzer et al. · Nature Medicine · 2016 · 243 citations · Full text

Hematological Malignancy, Chromatin, Mixed-phenotype Acute Leukemia +10

Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

Alan H. Shih, Yanwen Jiang, Cem Meydan et al. · Cancer Cell · 2015 · 242 citations · Full text

Chromatin, Combinatorial Epigenetic Gain, Chromatin Remodeling +11

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

Aaron D. Viny, Christopher J. Ott, Barbara Spitzer et al. · The Journal of Experimental Medicine · 2015 · 155 citations · Full text

Dose-dependent Role, Mixed-phenotype Acute Leukemia, Immunology +21

CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms

Sara C. Meyer, Matthew D. Keller, Sophia Chiu et al. · Cancer Cell · 2015 · 151 citations

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in <i>IDH2</i> - and <i>TET2</i> -Mutant Acute Myeloid Leukemia

Alan H. Shih, Cem Meydan, Kaitlyn Shank et al. · Cancer Discovery · 2017 · 110 citations · Full text