Nigel Austin

Pharmacological Actions of a Novel, High-Affinity, and Selective Human Dopamine D3 Receptor Antagonist, SB-277011-A

C. Reavill, Stephen G. Taylor, Martyn Wood et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 288 citations · Full text

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Renzo Mancuso, Gemma Fryatt, Madeleine Cleal et al. · Brain · 2019 · 224 citations · Full text

Immunology, Cell Death, Neurochemical Biomarkers +17

1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Roderick A. Porter, Wai N. Chan, Steven Coulton et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 165 citations · Full text

Functional Selectivity, Medicine, Receptor (Biochemistry) +4

Characterization of a CNS penetrant, selective M₁muscarinic receptor agonist, 77‐LH‐28‐1

Christopher J. Langmead, Nigel Austin, Clive L. Branch et al. · British Journal of Pharmacology · 2008 · 131 citations · Full text

Design and Synthesis of <i>trans</i>-<i>N</i>-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011):  A Potent and Selective Dopamine D₃ Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Geoffrey Stemp, Tracey Ashmeade, Clive L. Branch et al. · Journal of Medicinal Chemistry · 2000 · 129 citations · Full text

Pharmacotherapy, New Series, Experimental Pharmacology +19