Concepedia

Juliane Obst

JO

11

Publications

1.2K

Citations

11

H-Index

1971

Active since

Affiliations

University of Southampton(Current)

Southampton General Hospital

University of Oxford

Humboldt-Universität zu Berlin

Alzheimer’s Research UK

Juliane Obst is an author at University of Southampton specializing in medicine, neuroinflammation, and neurodegenerative diseases.

Top concepts

MedicineNeurologyNeuroimmunologyNeuroinflammationAlzheimer's DiseaseNeurodegenerative DiseasesImmunologyCell BiologyInflammationNeuroscience

Publications per year

1971–2025

11

Publications

11

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

Johannes vom Berg, Stefan Prokop, Kelly R. Miller et al. · Nature Medicine · 2012 · 403 citations

Inflammation, Neurodegenerative Diseases, Cognitive Decline +14

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology

Yanling Hu, Gemma Fryatt, Mohammadmersad Ghorbani et al. · Cell Reports · 2021 · 293 citations · Full text

Aging, Sustained Proliferation, Social Sciences +21

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Renzo Mancuso, Gemma Fryatt, Madeleine Cleal et al. · Brain · 2019 · 224 citations · Full text

Immunology, Cell Death, Neurochemical Biomarkers +17

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages

Hazel Hall‐Roberts, Devika Agarwal, Juliane Obst et al. · Alzheimer s Research & Therapy · 2020 · 63 citations · Full text

Interleukin‐12/23 deficiency differentially affects pathology in male and female Alzheimer's disease‐like mice

Pascale Eede, Juliane Obst, Eileen Benke et al. · EMBO Reports · 2020 · 35 citations · Full text

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