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Investigation of the mechanism of the dominant negative effect of mutations in the tyrosine kinase domain of the insulin receptor.

Rachel Levy-Toledano, Domenico Accili, Simeon I. Taylor

The EMBO Journal · 1994 · 44 citations · 36 references

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References

36

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

A Ullrich, Jeffrey R. Bell, E. Y. Chen et al. · Nature · 1985 · 2.3K citations

, , +12

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

Xiao‐Jian Sun, Paul Rothenberg, C. Ronald Kahn et al. · Nature · 1991 · 1.6K citations

, , +14

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

Yosef Yarden, Joseph Schlessinger · Biochemistry · 1987 · 628 citations

, , +9

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

Yosef Yarden, Joseph Schlessinger · Biochemistry · 1987 · 509 citations

, , +15

Two Mutant Alleles of the Insulin Receptor Gene in a Patient with Extreme Insulin Resistance

Takashi Kadowaki, Charles Bevins, Alessandro Cama et al. · Science · 1988 · 313 citations

, , +15