Concepedia

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

Xiao‐Jian Sun, Paul Rothenberg, C. Ronald Kahn, Jonathan Backer, Eiichi Araki, Peter A. Wilden, D A Cahill, Barry J. Goldstein, Morris F. White

Nature · 1991 · 1.6K citations · 25 references

DOI

Concepts

References

25

Synthetic oligonucleotide probes deduced from amino acid sequence data

Richard Lathe · Journal of Molecular Biology · 1985 · 761 citations

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Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

David R. Kaplan, Malcolm Whitman, Brian Schaffhausen et al. · Cell · 1987 · 669 citations

, , +17

Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

Morris F. White, Ruth Maron, C. Ronald Kahn · Nature · 1985 · 657 citations

, , +14

Purification and characterization of phosphoinositide 3-kinase from rat liver.

Catherine L. Carpenter, Brian Duckworth, K R Auger et al. · Journal of Biological Chemistry · 1990 · 638 citations · Full text

, , +17

Activation of phosphatidylinositol 3-kinase by insulin.

Neil B. Ruderman, Rosana Kapeller, Morris F. White et al. · Proceedings of the National Academy of Sciences · 1990 · 532 citations

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