Purification and characterization of phosphoinositide 3-kinase from rat liver.

Catherine L. Carpenter, Brian Duckworth, K R Auger, +3

Journal of Biological Chemistry

Protein SecretionMolecular BiologyCellular PhysiologyProtein PurificationProtein Expression +15

Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.

Peter Libby, José M. Ordovás, K R Auger, +3

PubMed

Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit

Catherine L. Carpenter, K R Auger, M. Chanudhuri, +4

Journal of Biological Chemistry

Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells.

Stephen J. Warner, K R Auger, Peter Libby

The Journal of Immunology

ImmunologyImmune RegulationImmunologic MechanismIl-1 ReleaseImmune System +18

Inducible interleukin-1 gene expression in human vascular smooth muscle cells.

Peter Libby, José M. Ordovás, Louis K. Birinyi, +2

Journal of Clinical Investigation

Endotoxin-stimulated SmcImmunologyImmune RegulationImmune SystemCellular Physiology +14

Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells.

Stephen J. Warner, K R Auger, Peter Libby

The Journal of Experimental Medicine

ImmunologyIl-1 ReleaseCellular PhysiologyInflammationInduces Interleukin 1 +15

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

Kathryn S. Campbell, Egon Ogris, Briant E. Burke, +5

Proceedings of the National Academy of Sciences

ImmunologyPathologyAntigen ProcessingCancer BiologyTumor Biology +15

A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors

Jean‐Charles Soria, Hui Gan, Sarah P. Blagden, +20

Annals of Oncology

Pharmacodynamic StudyMedicineCell AdhesionReceptor Tyrosine KinasePharmacology +5

Phosphatidylinositol 3-Kinase and Its Novel Product, Phosphatidylinositol 3-phosphate, Are Present in Saccharomyces cerevisiae

K R Auger, Christopher L. Carpenter, Lewis C. Cantley, +1

Journal of Biological Chemistry

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.

Christopher L. Carpenter, K R Auger, B C Duckworth, +3

Molecular and Cellular Biology

Molecular RegulationMolecular BiologyPathologyImmunologic MechanismCellular Physiology +17