Concepedia

Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation

Norimichi Koitabashi, Takeshi Aiba, Geoffrey G. Hesketh, J. G. Rowell, Manling Zhang, Eiki Takimoto, Gordon F. Tomaselli, David A. Kass

Journal of Molecular and Cellular Cardiology · 2009 · 176 citations · 38 references

DOI

Concepts

References

38

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Jeffery D. Molkentin, Jianrong Lu, Christopher L. Antos et al. · Cell · 1998 · 2.6K citations · Full text

, , +14

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Thomas Hofmann, Alexander G. Obukhov, Michael Schaefer et al. · Nature · 1999 · 1.5K citations

, , +16

A Mutation in the <i>TRPC6</i> Cation Channel Causes Familial Focal Segmental Glomerulosclerosis

Michelle P. Winn, Peter J. Conlon, Kelvin L. Lynn et al. · Science · 2005 · 1.1K citations

, , +17

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

Eiki Takimoto, Hunter C. Champion, Manxiang Li et al. · Nature Medicine · 2005 · 898 citations

, , +13

The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α<sub>1</sub>-Adrenoceptor–Activated Ca<sup>2+</sup>-Permeable Cation Channel

Ryuji Inoue, Takaharu Okada, Hitoshi Onoue et al. · Circulation Research · 2001 · 595 citations · Full text

, , +17