Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Jeffery D. Molkentin, Jianrong Lu, Christopher L. Antos et al. · Cell · 1998 · 2.6K citations · Full text

Cardiac Muscle, Transcriptional Regulation, Cardiomyopathy +8

Oral Sildenafil in the Treatment of Erectile Dysfunction

Irwin Goldstein, Tom F. Lue, Harin Padma-Nathan et al. · New England Journal of Medicine · 1998 · 2.1K citations

Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

Magdalena Juhaszova, Dmitry B. Zorov, Suhn-Hee Kim et al. · Journal of Clinical Investigation · 2004 · 988 citations · Full text

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

Orlando F. Bueno · The EMBO Journal · 2000 · 782 citations · Full text

Cardiac Muscle, Cardiomyopathy, Heart Failure +12

Calcineurin/NFAT Coupling Participates in Pathological, but not Physiological, Cardiac Hypertrophy

Benjamin J. Wilkins, Yan‐Shan Dai, Orlando F. Bueno et al. · Circulation Research · 2003 · 756 citations