Concepedia

Trpv6 Channel Function

TRPV6 Channel Function is a molecular physiological mechanism, specifically a calcium-selective ion channel activity, that mediates the apical uptake of extracellular calcium across the enterocyte membrane in the small intestine, distinguishing it among transcellular transport proteins by its high selectivity for calcium and vitamin D-regulated expression in intestinal epithelial cells.

224

Publications

18.5K

Citations

1.3K

Authors

458

Institutions

Publications per year

2017–2026

58

Parents

Publications

224

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Thomas Hofmann, Alexander G. Obukhov, Michael Schaefer et al. · Nature · 1999 · 1.5K citations

, , +16

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

Jochen Reiser, Krishna R. Polu, Clemens Möller et al. · Nature Genetics · 2005 · 858 citations · Full text

, , +12

Increased Vascular Smooth Muscle Contractility in <i>TRPC6</i><sup>−</sup><sup>/</sup><sup>−</sup> Mice

Alexander Dietrich, Michael Mederos y Schnitzler, Maik Gollasch et al. · Molecular and Cellular Biology · 2005 · 511 citations · Full text

, , +17

2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3

Hongzhen Hu, Qihai Gu, Chunbo Wang et al. · Journal of Biological Chemistry · 2004 · 504 citations · Full text

, , +16

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

Jian Xie, Seung‐Kuy Cha, Sung-Wan An et al. · Nature Communications · 2012 · 326 citations · Full text

, , +13

1–5 of 224

Authors

1.3K

  1. JG
    Joost G.J. Hoenderop

    Radboud University Nijmegen, Netherlands

    18 publications · 1.5K citations

    17

    h-index

  2. RJ
    René J.M. Bindels

    Radboud University Nijmegen, Netherlands

    16 publications · 1.3K citations

    15

    h-index

  3. VF
    Veit Flockerzi

    Saarland University, Germany

    14 publications · 1.2K citations

    14

    h-index

  4. MA
    Matthias A. Hediger

    Brigham and Women's Hospital, United States

    12 publications · 1.1K citations

    12

    h-index

  5. UW
    Ulrich Wissenbach

    Saarland University, Germany

    8 publications · 885 citations

    8

    h-index

1–5 of 1.3K

Institutions

458

  1. Radboud University Medical Center

    Nijmegen, The Netherlands

    18 h-index

    83 publications

    6.7K citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    18 h-index

    88 publications

    6.9K citations

  3. Saarland University

    Saarbrücken, Germany

    17 h-index

    73 publications

    6.1K citations

  4. University of Bern

    Bern, Switzerland

    12 h-index

    41 publications

    3.2K citations

  5. Inserm

    Paris, France

    9 h-index

    32 publications

    2.5K citations

  6. KU Leuven

    Leuven, Belgium

    8 h-index

    34 publications

    3.5K citations

  7. La Ligue Contre le Cancer

    Paris, France

    7 h-index

    34 publications

    3K citations

  8. Columbia University

    New York, United States

    7 h-index

    30 publications

    3.8K citations

1–8 of 458

Venues

  1. Journal of Biological Chemistry

    JBC · 18 publications · 2K citations

    18

    h-index

  2. Cell Calcium

    14 publications · 827 citations

    13

    h-index

  3. 6

    h-index

  4. Scientific Reports

    6 publications · 181 citations

    6

    h-index

  5. Journal of the American Society of Nephrology

    5 publications · 671 citations

    5

    h-index

1–5