Concepedia

Elucidating lipid nanoparticle properties and structure through biophysical analyses

Marshall S. Padilla, Sarah J. Shepherd, Andrew R. Hanna, Martin Kurnik, Xujun Zhang, Michelle Chen, James Byrnes, Ryann A. Joseph, Hannah M. Yamagata, Adele S. Ricciardi,

Nature Biotechnology · 2025 · 17 citations · 49 references

DOI

Concepts

References

49

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

Peter Schuck · Biophysical Journal · 2000 · 4K citations · Full text

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Determination of the regularization parameter in indirect-transform methods using perceptual criteria

Dmitri I. Svergun · Journal of Applied Crystallography · 1992 · 3.8K citations

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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Akin Akinc, Martin A. Maier, Muthiah Manoharan et al. · Nature Nanotechnology · 2019 · 1.6K citations · Full text

, , +16

Lipid-like materials for low-dose, in vivo gene silencing

Kevin T. Love, Kerry P. Mahon, Christopher G. Levins et al. · Proceedings of the National Academy of Sciences · 2010 · 965 citations · Full text

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Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

Katalin Karikó, Hiromi Muramatsu, János Ludwig et al. · Nucleic Acids Research · 2011 · 884 citations · Full text

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