Concepedia

Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD

Wesley Huang, Yuezhong Zhang, Nupur K. Das, Sumeet Solanki, Chesta Jain, Marwa O. El-Derany, Imhoi Koo, Hannah N. Bell, Noora Aabed, Rashi Singhal,

Nature Metabolism · 2025 · 33 citations · 38 references

DOIFull text

Open access

Concepts

References

38

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

, , +14

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker, Joseph M. Hendricks, Zhipeng Li et al. · Nature · 2019 · 3.6K citations · Full text

, , +9

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.8K citations · Full text

, , +7

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

James Kinchen, Hannah H. Chen, Kaushal Parikh et al. · Cell · 2018 · 738 citations · Full text

, , +17

Cells of the human intestinal tract mapped across space and time

Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts et al. · Nature · 2021 · 704 citations · Full text

, , +16