Concepedia

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker, Joseph M. Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter Tang, Melissa A. Roberts, Bingqi Tong, Thomas J. Maimone, Roberto Zoncu,

Nature · 2019 · 3.6K citations · 33 references

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33

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.5K citations · Full text

, , +12

FSP1 is a glutathione-independent ferroptosis suppressor

Sebastian Doll, Florêncio Porto Freitas, Ron Shah et al. · Nature · 2019 · 3.2K citations · Full text

, , +9

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Wan Seok Yang, Katherine J. Kim, Michael M. Gaschler et al. · Proceedings of the National Academy of Sciences · 2016 · 2.3K citations · Full text

, , +17

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Scott J. Dixon, Darpan N. Patel, Matthew Welsch et al. · eLife · 2014 · 2.1K citations · Full text

, , +13