Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

Hannah N. Bell, Ryan J. Rebernick, Joshua Goyert, +14

Cancer Cell

ProbioticDysbiosisRedox BalancePathologyColorectal Cancer +8

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron

Rashi Singhal, Sreedhar R. Mitta, Nupur K. Das, +9

Journal of Clinical Investigation

Iron MetabolismPathologyCell DeathCrc CellsCancer Biology +16

Bile salt hydrolase catalyses formation of amine-conjugated bile acids

Bipin Rimal, Stephanie L. Collins, Ceylan Tanes, +27

Nature

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer

Hannah N. Bell, Amanda K. Huber, Rashi Singhal, +23

Cell Metabolism

Cancer ImmunosurveillanceColorectal CancerMedicineCell BiologyTumor Microenvironment +1

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells

Andrew J. Schwartz, Joshua Goyert, Sumeet Solanki, +14

Nature Metabolism

Mitochondrial FunctionBiochemistryIron MetabolismLiver PhysiologySelenium Deficiency +10

Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation

Elise S. Hibdon, Nataliya Razumilava, Theresa M. Keeley, +4

Neoplasia

Dysregulated Amino Acid Sensing Drives Colorectal Cancer Growth and Metabolic Reprogramming Leading to Chemoresistance

Sumeet Solanki, Katherine Sanchez, Varun Ponnusamy, +7

Gastroenterology

Tumor BiologyBiochemistryMetabolic ReprogrammingMedicinePharmacology +5

Impact of dietary manganese on experimental colitis in mice

Eun‐Kyung Choi, Luisa Aring, Nupur K. Das, +6

The FASEB Journal

NutritionChronic Inflammatory DiseasesNutritional ManganeseImmunologyGastroenterology +15

GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress

Weihua Zhou, Zitong Zhao, Angelica Lin, +37

Cancer Discovery

Hypoxia via ERK Signaling Inhibits Hepatic PPARα to Promote Fatty Liver

Raja Gopal Reddy Mooli, Jessica Rodriguez, Shogo Takahashi, +4

Cellular and Molecular Gastroenterology and Hepatology