ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

Life Sciences, Bioinformatics, Oncology +12

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.5K citations

Medicine, Oncology, Pharmacology +15

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Peng Jiang, Shengqing Gu, Deng Pan et al. · Nature Medicine · 2018 · 5.6K citations · Full text

Life Sciences, Immunology, Oncology +14

Dictionary learning for integrative, multimodal and scalable single-cell analysis

Yuhan Hao, Tim Stuart, Madeline H. Kowalski et al. · Nature Biotechnology · 2023 · 4.8K citations · Full text

Life Sciences, Bioinformatics, Cell Biology +14

Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab

Nadeem Riaz, Jonathan J. Havel, Vladimir Makarov et al. · Cell · 2017 · 2.6K citations · Full text

Medicine, Immunology, Oncology +12