Insights into the molecular mechanisms, structure-activity relationships and application prospects of polysaccharides by regulating Nrf2-mediated antioxidant response

An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System

Sarkis K. Mazmanian, Cui Hua Liu, Arthur O. Tzianabos et al. · Cell · 2005 · 2.9K citations · Full text

Life Sciences, Immunology, Microbiology +16

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

Donna D. Zhang, Mark Hannink · Molecular and Cellular Biology · 2003 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

Tiara L.A. Kawahara, Eriko Michishita, Adam S. Adler et al. · Cell · 2009 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

Guang‐Hui Liu, Jing Qu, Xun Shen · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2008 · 668 citations

Life Sciences, Cell Biology, Molecular Biology +7

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

Sudhir Chowdhry, Yiguo Zhang, Michael McMahon et al. · Oncogene · 2012 · 635 citations · Full text

Life Sciences, Molecular Biology, Oncology +15