Evolutionarily Conserved and Nonconserved Cellular Localizations and Functions of Human SIRT Proteins

Eriko Michishita, Jean Y. Park, Jenna M. Burneskis, +2

Molecular Biology of the Cell

Nonconserved Cellular LocalizationsCellular LocalizationGenomic MechanismMolecular BiologyBiogerontology +17

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

Eriko Michishita, Ronald A. McCord, Elisabeth Berber, +12

Nature

Histone ModificationsChromatinHistone H3Chromatin StructureChromatin Remodeling +11

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

Tiara L.A. Kawahara, Eriko Michishita, Adam S. Adler, +8

Cell

Histone ModificationsChromatinTranscriptional RegulationChromatin StructureChromatin Remodeling +13

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

Xiaobing Shi, Tao Hong, Kay L. Walter, +18

Nature

Histone ModificationsChromatinTranscriptional RegulationChromatin StructureChromatin Remodeling +13

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

Ronald A. McCord, Eriko Michishita, Tao Hong, +9

Aging

Transcriptional activation of hTERT through the NF-κB pathway in HTLV-I–transformed cells

Uma Sinha-Datta, Izumi Horikawa, Eriko Michishita, +6

Blood

Induction of senescence-associated genes by 5-bromodeoxyuridine in HeLa cells

Toshikazu Suzuki, Sachi Minagawa, Eriko Michishita, +4

Experimental Gerontology

Lifespan ExtensionReductive StressCell DeathCellular SenescenceMedicine +4

Upregulation of the KIAA1199 gene is associated with cellular mortality

Eriko Michishita, Gabriela Rudd Garcés, J. Barrett, +1

Cancer Letters

MedicineGeneticsCell DeathGene CharacterizationMolecular Genetics +5

Differential cis-regulation of human versus mouse <i>TERT</i> gene expression <i>in vivo</i> : Identification of a human-specific repressive element

Izumi Horikawa, Y. Jeffrey Chiang, Tricia Patterson, +6

Proceedings of the National Academy of Sciences

Differential Cis-regulationGeneticsGenomic MechanismGene Regulatory NetworkEpigenetics +16

DNA Topoisomerase Inhibitors Induce Reversible Senescence in Normal Human Fibroblasts

Eriko Michishita, Kazuhiko Nakabayashi, Hideki Ogino, +3

Biochemical and Biophysical Research Communications

ChromatinGenome InstabilityNormal Human FibroblastsAnti-agingAging +6