Concepedia

SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

Wenxin Zhang, Junren Dai, Guixue Hou, Hao Liu, Shanliang Zheng, Xingwen Wang, Qingyu Lin, Yi Zhang, Minqiao Lu, Yafan Gong,

Molecular Cell · 2023 · 104 citations · 71 references

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71

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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Glutathione S-Transferases

William H. Habig, M. Pabst, William B. Jakoby · Journal of Biological Chemistry · 1974 · 18.1K citations · Full text

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Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.5K citations · Full text

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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker, Joseph M. Hendricks, Zhipeng Li et al. · Nature · 2019 · 3.6K citations · Full text

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