Concepedia

Targeted delivery of PROTAC-based prodrug activated by bond-cleavage bioorthogonal chemistry for microneedle-assisted cancer therapy

Jing Huang, Zhuo Yao, Bowen Li, Ping Yuan

Journal of Controlled Release · 2023 · 54 citations · 23 references

DOI

Concepts

References

23

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

Melissa L. Blackman, Maksim Royzen, Joseph M. Fox · Journal of the American Chemical Society · 2008 · 1.6K citations · Full text

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Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL

Wai‐Ching Hon, Michael Wilson, Karl Harlos et al. · Nature · 2002 · 746 citations

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Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras

Honorine Lebraud, David J. Wright, Christopher N. Johnson et al. · ACS Central Science · 2016 · 396 citations · Full text

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Light-Induced Protein Degradation with Photocaged PROTACs

Gang Xue, Kun Wang, Danli Zhou et al. · Journal of the American Chemical Society · 2019 · 344 citations

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PHOTACs enable optical control of protein degradation

Martin Reynders, Bryan S. Matsuura, Marleen Bérouti et al. · Science Advances · 2020 · 298 citations · Full text

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