Concepedia

2,5-disubstituted bicyclo[2.1.1]hexanes as rigidified cyclopentane variants

Shashwati Paul, Daniel Adelfinsky, Christophe Salomé, Thomas C. Fessard, M. Kevin Brown

Chemical Science · 2023 · 46 citations · 34 references

DOIFull text

Open access

Concepts

Abstract

-1,3-disubstituted cyclopentanes, common motifs in drugs. The scalable synthesis of these structures was enabled through the use of C-H functionalization logic and cycloaddition reactions.

References

34

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