Concepedia

Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling

Daniel J. Sanderson, Kelsie M. Rodriguez, Daniel S. Bejan, Ninni Elise Olafsen, Inga D. Bohn, Ana Kojic, Sunil K. Sundalam, Ivan Rodriguez Siordia, Anna K. Duell, Nancy Deng,

Cell chemical biology · 2022 · 42 citations · 27 references

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27

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

Junko Murai, Shar-yin N. Huang, Benu Brata Das et al. · Cancer Research · 2012 · 2.2K citations · Full text

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Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

Veit Rothhammer, Iván Mascanfroni, Lukas Bunse et al. · Nature Medicine · 2016 · 1.5K citations · Full text

, , +17

CRISPR-Mediated Tagging of Endogenous Proteins with a Luminescent Peptide

Marie K. Schwinn, Thomas Machleidt, Kris Zimmerman et al. · ACS Chemical Biology · 2017 · 455 citations · Full text

, , +13

ADP‐ribosyltransferases, an update on function and nomenclature

Bernhard Lüscher, Ivan Ahel, Matthias Altmeyer et al. · FEBS Journal · 2021 · 327 citations · Full text

, , +12

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1

Marie-France Langelier, Amanda A. Riccio, John M. Pascal · Nucleic Acids Research · 2014 · 279 citations · Full text

, , +17