International Immunopharmacology · 2022 · 29 citations · 35 references
Life SciencesImmunologyPathologyImmunopathologyInflammationInnate ImmunityGastrointestinal InflammationInflammasome ActivationInflammatory Bowel DiseaseInflammatory Cell ResponsesInflammatory SignalingNod-like ReceptorsInflammasome Inhibition MechanismsNlr Family Pyrin Domain-containing 3 InflammasomeNlrp3 Inflammasome
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A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
Zhenyu Zhong, Shuang Liang, Elsa Sánchez‐López et al. · Nature · 2018 · 1.2K citations
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
Humayun Sharif, Li Wang, Wei Li Wang et al. · Nature · 2019 · 796 citations · Full text
Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity
Hongbin He, Hua Jiang, Yun Chen et al. · Nature Communications · 2018 · 791 citations · Full text