Li Wang

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

Tomáš Čermák, Erin Doyle, Michelle Christian et al. · Nucleic Acids Research · 2011 · 2K citations · Full text

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome

Humayun Sharif, Li Wang, Wei Li Wang et al. · Nature · 2019 · 750 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +6

An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance

Ming He, Hou-Hsien Chiang, Hanzhi Luo et al. · Cell Metabolism · 2020 · 390 citations · Full text

Insulin Resistance, Metabolic Syndrome, Inflammation +13

TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance

Weigang He, Qiuyan Liu, Li Wang et al. · Molecular Immunology · 2007 · 338 citations

Cancer Immunosurveillance, Lung Inflammation, T-regulatory Cell +11

The p110α isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation

Jean J. Zhao, Hailing Cheng, Shidong Jia et al. · Proceedings of the National Academy of Sciences · 2006 · 223 citations · Full text

Oncogenic Transformation, Tumor Biology, Class Ia +16