Sphingosine kinase 1 promotes liver fibrosis by preventing miR‐19b‐3p‐mediated inhibition of CCR2

Tian Lan, Changzheng Li, Guizhi Yang, +8

Hepatology

Andrographolide ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated renal oxidative stress and inflammation via Akt/NF-κB pathway

Xiaoqian Ji, Changzheng Li, Yitao Ou, +10

Molecular and Cellular Endocrinology

Renal InflammationOxidative StressInflammationMetabolic SyndromeRenal Function +15

Disulfiram suppresses NLRP3 inflammasome activation to treat peritoneal and gouty inflammation

Wenmin Deng, Zhongjin Yang, Yue Hu, +3

Free Radical Biology and Medicine

InflammationRheumatologyAnti-inflammatoryAutoimmune DiseaseImmunology +9

Activation of Slit2-Robo1 signaling promotes liver fibrosis

Jianlan Chang, Tian Lan, Changzheng Li, +14

Journal of Hepatology

FibrosisSignal TransductionHepatologyLiver PhysiologyPathology +7

Osteopontin promotes collagen I synthesis in hepatic stellate cells by miRNA-129-5p inhibition

Yinghua Chen, Yitao Ou, Jiale Dong, +7

Experimental Cell Research

FibrosisDevelopmental BiologyHepatic Stellate CellsMirna-129-5p InhibitionMatrix Biology +4

Tanshinones inhibit NLRP3 inflammasome activation by alleviating mitochondrial damage to protect against septic and gouty inflammation

Yue Hu, Zhongjin Yang, Yitao Ou, +7

International Immunopharmacology

InflammationAnti-inflammatoryMitochondrial DamageAutoimmune DiseaseLipid Peroxidation +10

Artemisinin-derived artemisitene blocks ROS-mediated NLRP3 inflammasome and alleviates ulcerative colitis

Lei Hua, Shuli Liang, Yinghua Zhou, +11

International Immunopharmacology

InflammationAnti-inflammatoryImmunologyChronic InflammationPathology +3

Discovery of chalcone analogues as novel NLRP3 inflammasome inhibitors with potent anti-inflammation activities

Cheng Zhang, Yue Hu, Ping Sun, +9

European Journal of Medicinal Chemistry

InflammationAnti-inflammatoryMedicinePotent Anti-inflammation ActivitiesImmunology +6

Bortezomib inhibits NLRP3 inflammasome activation and NF-κB pathway to reduce psoriatic inflammation

Xiuhui Chen, Yanhong Chen, Yitao Ou, +9

Biochemical Pharmacology

InflammationPsoriatic InflammationAnti-inflammatoryMedicineImmunology +12

Seratrodast, a thromboxane A2 receptor antagonist, inhibits neuronal ferroptosis by promoting GPX4 expression and suppressing JNK phosphorylation

Ying Hao, Yitao Ou, Cheng Zhang, +6

Brain Research

Signal TransductionBiochemistryMedicineNeuropeptide ReceptorGpx4 Expression +7