Design, synthesis and antitumor activity evaluation of novel indole acrylamide derivatives as IMPDH inhibitors

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Satoshi Kofuji, Akiyoshi Hirayama, Alexander Otto Eberhardt et al. · Nature Cell Biology · 2019 · 177 citations · Full text

Medicine, Molecular Biology, Oncology +10

Consequences of IMP Dehydrogenase Inhibition, and its Relationship to Cancer and Apoptosis

Hiremagalur N. Jayaram, Michael Grusch, David A. Cooney et al. · Current Medicinal Chemistry · 1999 · 135 citations

Medicine, Oncology, Pharmacology +17

Expression of human IMP dehydrogenase types I and II in Escherichia coli and distribution in human normal lymphocytes and leukemic cell lines.

Yoshihiro Konno, Yutaka Natsumeda, María Aparecida Nagai et al. · Journal of Biological Chemistry · 1991 · 132 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Differentiation of cultured human breast cancer cells (AU‐565 and MCF‐7) associated with loss of cell surface <i>HER‐2/neu</i> antigen

Sarah Bacus, Kaoru Kiguchi, C. Richter King et al. · Molecular Carcinogenesis · 1990 · 116 citations

Life Sciences, Cell Biology, Molecular Biology +13

Inosine monophosphate dehydrogenase and myeloid cell maturation

RD Knight, J Mangum, Lucas Dl et al. · Blood · 1987 · 75 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11