Concepedia

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Satoshi Kofuji, Akiyoshi Hirayama, Alexander Otto Eberhardt, Risa Karakida Kawaguchi, Yuki Sugiura, Oltea Sampetrean, Yoshiki Ikeda, Mikako Warren, Naoya Sakamoto, Shuji Kitahara,

Nature Cell Biology · 2019 · 177 citations · 48 references

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48

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

J. Edwin Seegmiller, Frederick M. Rosenbloom, William N. Kelley · Science · 1967 · 1.2K citations

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Nucleolar proteome dynamics

Jens Andersen, Yun Wah Lam, Anthony K. L. Leung et al. · Nature · 2005 · 1.1K citations

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

Denis Drygin, Amy Lin, Josh Bliesath et al. · Cancer Research · 2010 · 621 citations

, , +17

Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo

Isaac Marin‐Valencia, Chendong Yang, Tomoyuki Mashimo et al. · Cell Metabolism · 2012 · 532 citations · Full text

, , +14

A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells

Robert Y. L. Tsai, Ronald D.G. McKay · Genes & Development · 2002 · 454 citations · Full text

, , +17