Hiremagalur N. Jayaram

Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-β-d-ribofuranosylthiazole-4-carboxamide NSC 286193)

Hiremagalur N. Jayaram, Robert L. Dion, Robert I. Glazer et al. · Biochemical Pharmacology · 1982 · 144 citations

Medicinal Chemistry, Initial Studies, Biochemistry +8

Consequences of IMP Dehydrogenase Inhibition, and its Relationship to Cancer and Apoptosis

Hiremagalur N. Jayaram, Michael Grusch, David A. Cooney et al. · Current Medicinal Chemistry · 1999 · 134 citations

Biochemically directed therapy of leukemia with tiazofurin, a selective blocker of inosine 5'-phosphate dehydrogenase activity.

Guido Tricot, Hiremagalur N. Jayaram, Elizabeth Lapis et al. · PubMed · 1989 · 127 citations

Mixed-phenotype Acute Leukemia, Pharmacotherapy, Chemical Biology +18

The conversion of 2-β-D-ribofuranosylthiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties

David A. Cooney, Hiremagalur N. Jayaram, Gulilat Gebeyehu et al. · Biochemical Pharmacology · 1982 · 121 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +6

Conversion of 2-β-D-ribofuranosylselenazole-4-carboxamide to an analogue of nad with potent imp dehydrogenase-inhibitory properties

Hiremagalur N. Jayaram, Gurpreet S. Ahluwalia, Robert L. Dion et al. · Biochemical Pharmacology · 1983 · 104 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +6