Biotransformation of phenytoin in the electrochemically-driven CYP2C19 system

Evaluation of Atypical Cytochrome P450 Kinetics with Two-Substrate Models:  Evidence That Multiple Substrates Can Simultaneously Bind to Cytochrome P450 Active Sites

Ken Korzekwa, N. Krishnamachary, Magang Shou et al. · Biochemistry · 1998 · 519 citations

Medicine, Pharmacokinetics, Pharmacology +17

Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications

Zhong Li, Yuanyuan Jiang, F. Peter Guengerich et al. · Journal of Biological Chemistry · 2020 · 251 citations · Full text

Engineering, Biochemistry, Biotechnology +17

Direct electron injection from electrodes to cytochrome P450cam in biomembrane-like films

Zhe Zhang, Alaa-Eldin F. Nassar, Zhongqing Lu et al. · Journal of the Chemical Society Faraday Transactions · 1997 · 170 citations

Engineering, Biochemistry, Biocatalysis +16

Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine

Gina M. Giancarlo, Karthik Venkatakrishnan, Brian Granda et al. · European Journal of Clinical Pharmacology · 2001 · 102 citations

Medicine, Pharmacokinetics, Pharmacology +9

Drug–drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4

Sheila J. Sadeghi, Silvia Ferrero, Giovanna Di Nardo et al. · Bioelectrochemistry · 2012 · 51 citations · Full text

Medicine, Biochemistry, Pharmacology +16