Ken Korzekwa

Evaluation of Atypical Cytochrome P450 Kinetics with Two-Substrate Models:  Evidence That Multiple Substrates Can Simultaneously Bind to Cytochrome P450 Active Sites

Ken Korzekwa, N. Krishnamachary, Magang Shou et al. · Biochemistry · 1998 · 516 citations

Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8.

Atiqur Rahman, Ken Korzekwa, James Grogan et al. · PubMed · 1994 · 391 citations

Pharmaceutical Science, Pharmaceutical Chemistry, Aldehyde Dehydrogenase +15

Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site

Magang Shou, James Grogan, Julie Mancewicz et al. · Biochemistry · 1994 · 349 citations

Aldo-keto Reductase, Signal Recognition, Molecular Biology +18

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

David J. Waxman, D P Lapenson, Toshifumi Aoyama et al. · Archives of Biochemistry and Biophysics · 1991 · 324 citations

Biochemistry, Endocrine Mechanism, Medicine +6

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.

Mary V. Relling, J.F. Nemec, Erin G. Schuetz et al. · Molecular Pharmacology · 1994 · 180 citations