Brian Granda

Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice

Xiaojun Liu, Shuguang Jiang, Chongyun Fang et al. · Cancer Research · 2015 · 554 citations · Full text

Immunology, Immunoediting, Immune Cell Therapy +17

Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir

Lisa L. von Moltke, David J. Greenblatt, Jeffrey M. Grassi et al. · The Journal of Clinical Pharmacology · 1998 · 250 citations

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

Julia K. Kurash, Hong Lei, Qiong Shen et al. · Molecular Cell · 2008 · 204 citations · Full text

Chromatin, Epigenetic Change, Dna Methylation +6

Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram.

Lisa L. von Moltke, David J. Greenblatt, Gina M. Giancarlo et al. · PubMed · 2001 · 199 citations

Microm Quinidine, Secondary Metabolite, Pharmacotherapy +17

Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells

Nathan Singh, Noelle V. Frey, Boris Engels et al. · Nature Medicine · 2021 · 189 citations · Full text

Antigen-independent Activation, Autoimmune Disease, Immunology +8