Concepedia

Secretion into Milk of the Main Metabolites of the Anthelmintic Albendazole Is Mediated by the ABCG2/BCRP Transporter

Esther Blanco–Paniagua, Laura Álvarez–Fernández, Alba M. García‐Lino, Ana I. Álvarez, Gracia Merino

Antimicrobial Agents and Chemotherapy · 2022 · 14 citations · 50 references

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Concepts

Abstract

Albendazole (ABZ) is an anthelmintic with a broad-spectrum activity, widely used in human and veterinary medicine. ABZ is metabolized in all mammalian species to albendazole sulfoxide (ABZSO), albendazole sulfone (ABZSO 2 ) and albendazole 2-aminosulphone (ABZSO 2 -NH 2 ).

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