Pauline Breedveld

The Effect of Bcrp1 (Abcg2) on the <i>In vivo</i> Pharmacokinetics and Brain Penetration of Imatinib Mesylate (Gleevec): Implications for the Use of Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors to Enable the Brain Penetration of Imatinib in Patients

Pauline Breedveld, Dick Pluim, Greta Cipriani et al. · Cancer Research · 2005 · 349 citations

Brain Penetration, Pharmacotherapy, Glioma +16

Mechanism of the Pharmacokinetic Interaction between Methotrexate and Benzimidazoles

Pauline Breedveld, Noam Zelcer, Dick Pluim et al. · Cancer Research · 2004 · 232 citations · Full text

Pharmaceutical Science, Drug Targeting, Mtx Transport +13

Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)

Noam Zelcer, Maarten T. Huisman, Glen Reid et al. · Journal of Biological Chemistry · 2003 · 198 citations · Full text

Breast Cancer Resistance Protein (Bcrp1/Abcg2) Limits Net Intestinal Uptake of Quercetin in Rats by Facilitating Apical Efflux of Glucuronides

Aloys L.A. Sesink, Ilja C.W. Arts, Vincent C. J. de Boer et al. · Molecular Pharmacology · 2005 · 123 citations · Full text

The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models

Pauline Breedveld, Dick Pluim, Greta Cipriani et al. · Molecular Pharmacology · 2006 · 107 citations