Pauline Breedveld

The Effect of Bcrp1 (Abcg2) on the <i>In vivo</i> Pharmacokinetics and Brain Penetration of Imatinib Mesylate (Gleevec): Implications for the Use of Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors to Enable the Brain Penetration of Imatinib in Patients

Pauline Breedveld, Dick Pluim, Greta Cipriani et al. · Cancer Research · 2005 · 351 citations

Medicine, Pharmacokinetics, Pharmacology +16

Mechanism of the Pharmacokinetic Interaction between Methotrexate and Benzimidazoles

Pauline Breedveld, Noam Zelcer, Dick Pluim et al. · Cancer Research · 2004 · 233 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)

Noam Zelcer, Maarten T. Huisman, Glen Reid et al. · Journal of Biological Chemistry · 2003 · 198 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Breast Cancer Resistance Protein (Bcrp1/Abcg2) Limits Net Intestinal Uptake of Quercetin in Rats by Facilitating Apical Efflux of Glucuronides

Aloys L.A. Sesink, Ilja C.W. Arts, Vincent C. J. de Boer et al. · Molecular Pharmacology · 2005 · 125 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models

Pauline Breedveld, Dick Pluim, Greta Cipriani et al. · Molecular Pharmacology · 2006 · 109 citations

Medicine, Biochemistry, Pharmacology +17