Concepedia

The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models

Pauline Breedveld, Dick Pluim, Greta Cipriani, Femke Dahlhaus, Maria A.J. van Eijndhoven, Cornelia J. F. de Wolf, Annemieke Kuil, Jos H. Beijnen, George L. Scheffer, Gerrit Jansen,

Molecular Pharmacology · 2006 · 109 citations · 40 references

DOI

Concepts

References

40

A multidrug resistance transporter from human MCF-7 breast cancer cells

L. Austin Doyle, Weidong Yang, Lynne V. Abruzzo et al. · Proceedings of the National Academy of Sciences · 1998 · 2.3K citations

, , +16

Clinical pharmacokinetics; concepts and applications

General Pharmacology The Vascular System · 1989 · 2.2K citations

, , +12

Acid pH in tumors and its potential for therapeutic exploitation.

Ian F. Tannock, Daniela Rotin · PubMed · 1989 · 1.6K citations

, , +16

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

Marc Maliepaard, George L. Scheffer, Ian F. Faneyte et al. · PubMed · 2001 · 1.1K citations

, , +14

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

Arnold van Loevezijn, Jeany M Lakhai, Martin van der Valk et al. · PubMed · 2002 · 687 citations

, , +17