Molecular Biology Reports · 2022 · 33 citations · 48 references
Life SciencesGeneticsMolecular GeneticsGenetic EngineeringGenome EditingMolecular BiotechnologyCrispr-based EngineeringCrispr-cas SystemsGuide Rna DesignTherapeutic Genome EditingCrispr-based Genome EngineeringCrispr-cas9 Genome EditingCrispr-cas9-mediated Repair
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Cell · 2015 · 4.9K citations · Full text