Concepedia

SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway

Kun Fang, Sha Du, Dachuan Shen, Zhipeng Xiong, Ke Jiang, Dapeng Liang, Jianxin Wang, Huizhe Xu, Lulu Hu, Xingyue Zhai,

iScience · 2022 · 46 citations · 32 references

DOIFull text

Open access

Concepts

Abstract

. Together, our findings uncover SUFU as a novel regulator in ferroptosis sensitivity.

References

32

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.5K citations · Full text

, , +12

Role of YAP/TAZ in mechanotransduction

Sirio Dupont, Leonardo Morsut, Mariaceleste Aragona et al. · Nature · 2011 · 5.9K citations · Full text

, , +5

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

, , +14

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth et al. · Nature Cell Biology · 2014 · 3.6K citations

, , +10