Matrix Elasticity Directs Stem Cell Lineage Specification

Adam J. Engler, Shamik Sen, H. Lee Sweeney, +1

Cell

Lineage PlasticityDevelopmental BiologyMedicineAdult Stem CellStem Cell Research +5

Geometric Control of Cell Life and Death

Christopher S. Chen, Milan Mrksich, Sui Huang, +2

Science

Tissue EngineeringCell ExtensionEngineeringCell AdhesionCell Death +18

Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

Rowena McBeath, Dana M. Pirone, Celeste M. Nelson, +2

Developmental Cell

Cytoskeletal TensionLineage PlasticityDevelopmental BiologyCell LineageMedicine +7

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao, Xiaomu Wei, Weiquan Li, +13

Genes & Development

TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao, Xin Ye, Jindan Yu, +9

Genes & Development

Hippo PathwayDevelopmental BiologySignaling PathwayYap Transcription CoactivatorGenetics +8

Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals

Jixin Dong, Georg Feldmann, Jianbin Huang, +7

Cell

BiologyPattern FormationNatural SciencesEvolutionary BiologyMechanism (Biology) +5

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

Andrea Bild, Guang Yao, Jeffrey T. Chang, +12

Nature

Oncogenic Pathway SignaturesRadiation OncologySystems BiologyOncologyEngineering +10

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

Penney M. Gilbert, Karen Havenstrite, Klas E. G. Magnusson, +7

Science

Tissue EngineeringRegenerationSubstrate ElasticityEngineeringMuscle Function +19

Actin Dynamics Control SRF Activity by Regulation of Its Coactivator MAL

Francesc Miralles, Guido Posern, Alexia-Ileana Zaromytidou, +1

Cell

Protein FunctionSignal TransductionBiochemistryMolecular RegulationNatural Sciences +9

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

Jianping Fu, Yang-Kao Wang, Michael T. Yang, +4

Nature Methods

Tissue EngineeringMechanobiologyEngineeringBiomechanicsCell Motility +11