Concepedia

Trans-channel fluorescence learning improves high-content screening for Alzheimer’s disease therapeutics

Daniel R. Wong, Jay C. Conrad, Noah R. Johnson, Jacob I. Ayers, Annelies Laeremans, Joanne C. Lee, Jisoo Lee, Stanley B. Prusiner, Sourav Bandyopadhyay, Atul J. Butte,

Nature Machine Intelligence · 2022 · 13 citations · 35 references

DOIFull text

Open access

Concepts

References

35

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht et al. · Genome biology · 2006 · 5.5K citations · Full text

, , +14

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

, , +15

Transmission and spreading of tauopathy in transgenic mouse brain

Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther et al. · Nature Cell Biology · 2009 · 1.8K citations · Full text

, , +12

Benchmarking Sets for Molecular Docking

Niu Huang, Brian K. Shoichet, John J. Irwin · Journal of Medicinal Chemistry · 2006 · 1.3K citations · Full text

, , +17

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

Michel Goedert, Ross Jakes, M. G. Spillantini et al. · Nature · 1996 · 1K citations

, , +15