Jacob I. Ayers

Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice

Amanda N. Sacino, Mieu Brooks, M. Albert Thomas et al. · Proceedings of the National Academy of Sciences · 2014 · 325 citations · Full text

Neurogenomics, Synaptic Transmission, Neurological Progress +24

Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components

Evan Lester, Felicia K. Ooi, Nadine Bakkar et al. · Neuron · 2021 · 202 citations · Full text

Chromatin, Rna Processing, Protein Folding +11

Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

Jacob I. Ayers, Susan Fromholt, Veronica O’Neal et al. · Acta Neuropathologica · 2015 · 142 citations · Full text

Neuroanatomical Pathways, Neurodegenerative Diseases, Creutzfeldt-jakob Disease +10

Experimental transmissibility of mutant SOD1 motor neuron disease

Jacob I. Ayers, Susan Fromholt, Morgan Koch et al. · Acta Neuropathologica · 2014 · 122 citations

Amyotrophic Lateral Sclerosis, Motor Dysfunction, Experimental Neuropathology +7

The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

Jacob I. Ayers, Charles R. Schutt, Ronald A. Shikiya et al. · PLoS Pathogens · 2011 · 109 citations · Full text